Gastrointestinal Stromal Tumor-GIST
Gastrointestinal Stromal Tumors (GISTs) are rare tumors of the digestive tract, typically arising in the stomach or small intestine.
They develop from interstitial cells of Cajal and may be asymptomatic in early stages. Advanced tumors can cause bleeding, obstruction, or pain. Treatment involves surgery and targeted therapies like imatinib to prevent recurrence.
Causes and Risk Factors of GIST
GIST arises from mutations in specific genes, affecting cell growth.
- Genetic mutations: Mutations in KIT or PDGFRA genes are common.
- Age: Usually diagnosed in people over 50.
- No clear lifestyle cause: Diet and exercise are not linked to GIST.
Symptoms and Warning Signs
Early tumors may remain silent, but symptoms appear as tumor grows.
- Abdominal pain or fullness
- Gastrointestinal bleeding: Black stools or vomiting blood
- Fatigue due to anemia
- Bowel obstruction in advanced cases
Treatment Options for GIST
Treatment is aimed at removing tumors and preventing recurrence.
- Surgical resection: Complete removal of the tumor with safe margins.
- Targeted therapy: Imatinib or similar medications for advanced or high-risk cases.
- Regular follow-up imaging to detect recurrence.
Why Choose Us for Gastrointestinal Stromal Tumors
CureU Healthcare offers experienced surgical oncology teams, precision targeted therapy, and continuous monitoring to ensure optimal outcomes.
Conclusion
GISTs are rare but manageable with early diagnosis and expert care. CureU Healthcare ensures surgical precision and personalized treatment strategies.
