Celiac Disease
Celiac disease is a chronic autoimmune disorder triggered by gluten consumption in genetically predisposed individuals.
The immune response damages the intestinal lining, leading to malabsorption, digestive discomfort, and nutritional deficiencies.
Overview And Clinical Background
Celiac disease causes inflammation of the small intestine due to gluten ingestion.
It’s lifelong but manageable with a strict gluten-free diet.
- Mechanism: Gluten triggers an immune attack on intestinal villi.
- Damage leads to poor absorption of essential nutrients.
- Prevalence: Affects about 1% of the population globally.
Symptoms, Signs And Presentation
Symptoms vary widely and can be digestive or systemic.
Some patients remain asymptomatic for years.
- Digestive symptoms: Diarrhea, bloating, and weight loss.
- Fatigue, irritability, and anemia due to malabsorption.
- Long-term risk: Untreated cases may cause osteoporosis or infertility.
Diagnosis Methods And Investigations
Diagnosis involves antibody testing and intestinal biopsy.
Genetic testing helps confirm susceptibility.
- Serologic tests: tTG-IgA and EMA antibodies confirm autoimmune reaction.
- Endoscopy with biopsy: Shows villous atrophy and mucosal inflammation.
- Genetic markers HLA-DQ2/DQ8 support diagnosis.
Treatment Options And Surgical Techniques
There’s no cure, but a strict lifelong gluten-free diet ensures full recovery of intestinal lining.
Nutritional supplementation helps correct deficiencies.
- Dietary management: Eliminate all sources of wheat, barley, and rye.
- Supplements: Iron, calcium, and vitamin D may be needed initially.
- Regular monitoring ensures mucosal healing.
Recovery, Risks And Prognosis
Symptoms often improve within weeks of dietary control.
Long-term prognosis is excellent with strict gluten avoidance.
Why Choose Us
CureU Healthcare provides personalized diet guidance, accurate testing, and long-term management to restore gut health.
Our multidisciplinary team ensures complete lifestyle support.
Conclusion
Celiac disease is highly manageable with awareness and discipline.
A gluten-free life leads to full recovery and well-being.
